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Am J Clin Nutr. 2010 Dec;92(6):1468-77. doi: 10.3945/ajcn.2010.29512. Epub 2010 Oct 27.

Rice intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study.

Author information

1
Department of Epidemiology and International Health, International Clinical Research Center, National Center for Global Health and Medicine, Tokyo, Japan. nanri@ri.ncgm.go.jp

Abstract

BACKGROUND:

Refined carbohydrates have been suggested to deteriorate glucose metabolism; however, whether persons with elevated intakes of white rice, which is a major staple food for the Japanese, experience increased risk of developing type 2 diabetes remains unclear.

OBJECTIVE:

We prospectively investigated the association between white rice intake and risk of type 2 diabetes.

DESIGN:

Participants were 25,666 men and 33,622 women aged 45-75 y who participated in the second survey of the Japan Public Health Center-based Prospective Study and who had no prior history of diabetes. We ascertained food intake by using a validated 147-item food-frequency questionnaire. Odds ratios of self-reported, physician-diagnosed type 2 diabetes over 5 y were estimated by using logistic regressions.

RESULTS:

A total of 1103 new cases of type 2 diabetes were self-reported. There was a significant association between rice intake and an increased risk of type 2 diabetes in women; the multivariate-adjusted odds ratio for the highest compared with lowest quartiles of rice intake was 1.65 (95% CI: 1.06, 2.57; P for trend = 0.005). In men, the association was unclear, although there was a suggestion of a positive association in persons who were not engaged in strenuous physical activity (P for trend = 0.08).

CONCLUSIONS:

Elevated intake of white rice is associated with an increased risk of type 2 diabetes in Japanese women. The finding that is suggestive of a positive association of rice intake in physically inactive men deserves further investigation.

PMID:
20980490
DOI:
10.3945/ajcn.2010.29512
[Indexed for MEDLINE]

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