Format

Send to

Choose Destination
Immunol Cell Biol. 1990 Dec;68 ( Pt 6):405-8.

The effect of glutamine on murine splenic leukocyte responses to T and B cell mitogens.

Author information

1
University Department of Microbiology, Queen Elizabeth II Medical Centre, Nedlands, Western Australia.

Abstract

Murine splenic leukocytes cannot be stimulated to synthesize [3H]-DNA by various concentrations of either the T cell mitogens, Concanavalin-A (Con-A) or phytohaemagglutinin (PHA) or the B cell mitogen, lipopolysaccharide (LPS), unless glutamine is present in the culture medium. The optimum concentration of the T cell mitogens (Con-A, PHA) remained constant for all levels of glutamine while that of the B cell mitogen (LPS) increased as the concentration of glutamine in the medium increased.

PMID:
2097296
DOI:
10.1038/icb.1990.54
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center