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Curr Biol. 2010 Oct 26;20(20):R888-91. doi: 10.1016/j.cub.2010.09.035.

Calcium signalling: fishing out molecules of mitochondrial calcium transport.

Author information

1
Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA. Gyorgy.Hajnoczky@jefferson.edu

Abstract

Cellular energy metabolism, survival and death are controlled by mitochondrial calcium signals originating in the cytoplasm. Now, RNAi studies link three proteins - MICU1, NCLX and LETM1 - to the previously unknown molecular mechanism of mitochondrial calcium transport.

PMID:
20971432
PMCID:
PMC3174682
DOI:
10.1016/j.cub.2010.09.035
[Indexed for MEDLINE]
Free PMC Article
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