Abstract
The chromosomal passenger complex (CPC) is a major regulator of mitotic and meiotic chromosome segregation. Three recent papers now elucidate the mechanisms that determine the localization of the CPC to the inner centromere.
Copyright © 2010 Elsevier Ltd. All rights reserved.
MeSH terms
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Aurora Kinases
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Centromere / metabolism*
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Chromosomal Proteins, Non-Histone / metabolism*
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Chromosome Segregation / physiology*
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Microtubule-Associated Proteins / metabolism*
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Models, Biological
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Multiprotein Complexes / genetics
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Multiprotein Complexes / metabolism*
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Phosphorylation
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Protein Serine-Threonine Kinases / metabolism*
Substances
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Chromosomal Proteins, Non-Histone
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Microtubule-Associated Proteins
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Multiprotein Complexes
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Aurora Kinases
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Protein Serine-Threonine Kinases