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Am J Ophthalmol. 2010 Dec;150(6):917-24. doi: 10.1016/j.ajo.2010.06.037. Epub 2010 Oct 20.

Prevalence of glaucoma in North China: the Beijing Eye Study.

Author information

1
Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Abstract

PURPOSE:

To assess the prevalence of glaucoma in adult Chinese.

DESIGN:

Population-based study.

METHODS:

The Beijing Eye Study in 2001 included 4439 subjects with an age of 40+ years. Glaucoma was determined using the ISGEO (International Society of Geographical and Epidemiological Ophthalmology) classification scheme.

RESULTS:

Glaucoma was detected in 158 subjects (3.7%, 95% confidence interval [CI] 3.1%-4.2%), in which open-angle glaucoma (OAG), primary angle-closure glaucoma (PACG), and secondary glaucoma (SG) accounted for 2.6% (95% CI 2.1%-3.0%), 1.0% (95% CI 0.7%-1.3%), and 0.07% (95% CI 0%-0.1%), respectively. The overall glaucoma prevalence for the age groups of 40 to 49 years, 50 to 59 years, 60 to 69 years, and 70+ years was 2.2%, 2.5%, 4.4%, and 9.5%, respectively. Glaucoma prevalence increased significantly with age (P = .001), myopic refractive error (P < .001), and intraocular pressure (P < .001). The age-standardized prevalence of OAG, PACG, and SG was 2.5%, 1.0%, and 0.1%, respectively. Prevalence of glaucoma-related bilateral blindness or unilateral blindness was significantly (P = .02 and P = .03) higher in PACG than in OAG. Frequency of glaucoma-associated blindness and low vision was significantly higher in the rural area than in the urban region (6/62 vs 2/96, P = .04).

CONCLUSIONS:

In the adult population of Greater Beijing, glaucoma prevalence was 3.6% and increased with age, myopic refractive error, and intraocular pressure. Glaucoma prevalence of 3.6% was comparable with figures from Caucasian populations. The ratio of OAG to PACG of 2.6:1 agrees with recent other studies from East Asia. Glaucoma-related blindness and low vision occurred significantly more often in PACG than in OAG.

PMID:
20970107
DOI:
10.1016/j.ajo.2010.06.037
[Indexed for MEDLINE]

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