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Bull NYU Hosp Jt Dis. 2010;68(3):199-203.

Gout and its comorbidities.

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New York University School of Medicine, NYU Hospital for Joint Diseases, New York, NY 10003, USA.


Gout is a chronic disease in which excessively high levels of serum urate (hyperuricemia) result in tissue depositions of sodium urate crystals and intermittent inflammatory attacks. Patients who have gout frequently experience a range of comorbidities, which complicates management and affects long-term prognosis. We review some of the more important of these comorbidities and consider the extent to which gout or hyperuricemia may be either a consequence or a cause of these related conditions. In addition, we briefly consider several neurological conditions in which the presence of gout or a high serum urate level may be associated with less disease, rather than more.

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