Format

Send to

Choose Destination
See comment in PubMed Commons below
AIDS. 2011 Jan 2;25(1):115-8. doi: 10.1097/QAD.0b013e328340a1e7.

Alpha interferon administration during structured interruptions of combination antiretroviral therapy in patients with chronic HIV-1 infection: INTERVAC ANRS 105 trial.

Author information

1
Hôpital Antoine Béclère APHP, Université Paris-Sud, Clamart, France. francois.boue@abc.aphp.fr

Abstract

Interferon-α administration during structured treatment interruptions (STIs) was studied in a phase III trial. We randomized 168 chronically infected HIV undetectable under combined antiretroviral therapy patients to have three STIs with or without α-interferon. The number of patients who had to resume treatment during post-STI follow-up was not significantly different between the two arms. Patients with a low CD4 nadir and a high baseline HIV-DNA had a higher risk of treatment resumption in the interferon arm.

PMID:
20962614
DOI:
10.1097/QAD.0b013e328340a1e7
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wolters Kluwer
    Loading ...
    Support Center