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Diabetes Res Clin Pract. 2011 May;92(2):145-52. doi: 10.1016/j.diabres.2010.09.023. Epub 2010 Oct 20.

Effect of pharmacist intervention on glycemic control in diabetes.

Author information

1
University of Connecticut School of Pharmacy, Storrs, CT 06102-5037, United States.

Abstract

AIM:

To conduct a meta-analysis evaluating the effect of pharmacist intervention on glycemic control.

METHODS:

A systematic search of Medline and CENTRAL was conducted from the earliest possible date through June 2010. Trials were included if they were randomized controlled trials in a diabetic population, evaluated any form of pharmacist intervention and reported data on hemoglobin A1C (A1C). A random-effects model was used to calculate weighted mean differences (WMDs) and 95% confidence intervals.

RESULTS:

Fourteen trials (n = 2073) evaluating the effect of pharmacist intervention on glycemic control were identified. Pharmacist intervention significantly lowered A1C (n = 14 trials, WMD -0.76%, 95%CI -1.06 to -0.47) and fasting blood glucose (FBG) (n = 4 trials, WMD -29.32 mg/dL, 95%CI -39.54 to -19.10). A moderate to high degree of statistical heterogeneity was observed in these analyses (I(2) ≥ 44.1% for both).

CONCLUSIONS:

Our findings demonstrate statistically and clinically significant associations between pharmacist intervention and improvement in glycemic control.

PMID:
20961643
DOI:
10.1016/j.diabres.2010.09.023
[Indexed for MEDLINE]

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