Format

Send to

Choose Destination
See comment in PubMed Commons below
J Fam Psychol. 2010 Oct;24(5):513-21. doi: 10.1037/a0020835.

Differential susceptibility to parenting among African American youths: testing the DRD4 hypothesis.

Author information

1
Institute for Behavioral Research, University of Georgia, Athens, GA 30602, USA. srhbeach@uga.edu

Abstract

To test the differential susceptibility to parenting hypothesis, a 4-wave, randomized prevention design was used to examine the impact of the Strong African American Families program on past-month substance use across 29 months as a function of DRD4 genotype. Youths (N = 337; M age = 11.65 years) were assigned randomly to treatment condition. Those carrying a 7-repeat allele showed greater differential response to intervention vs. control than those with two 4-repeat alleles. Control youths but not treatment youths with a 7-repeat allele reported increases in past-month substance use across the 29-month study period, but this pattern did not emerge for those with the 4-repeat allele. Supporting the differential susceptibility to parenting hypothesis, the results suggest a greater preventive effect for youths carrying a 7-repeat allele, a role for DRD4 in the escalation of substance use during adolescence, and potential for an enhanced understanding of early-onset substance use.

PMID:
20954761
PMCID:
PMC2958690
DOI:
10.1037/a0020835
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Psychological Association Icon for PubMed Central
    Loading ...
    Support Center