Format

Send to

Choose Destination
Curr Opin Microbiol. 2010 Dec;13(6):753-7. doi: 10.1016/j.mib.2010.09.014. Epub 2010 Oct 13.

Protein localization by recognition of membrane curvature.

Author information

1
Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States. ramamurthiks@mail.nih.gov

Abstract

Bacteria often sort proteins to specific subcellular locations, but many of the chemical beacons that specify those sites and subsequently recruit proteins have not been identified. Recent reports suggest that some bacterial proteins localize to specific subcellular sites by recognizing either convex or concave membrane curvature. Thus, degrees of membrane curvature, dictated by the shape of the cell, can define a geometric cue for the recruitment of curvature-sensing proteins.

PMID:
20951078
PMCID:
PMC2994992
DOI:
10.1016/j.mib.2010.09.014
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center