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Pediatr Blood Cancer. 2010 Dec 15;55(7):1420-2. doi: 10.1002/pbc.22641.

Focal nodular hyperplasia in pediatric patients with and without oncologic history.

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  • 1Pediatric Surgery Department, University Hospital of Padua, Padua, Italy.


The diagnosis of FNH is warranted by the possibility of avoiding unnecessary hepatic resections. The 18 patients of our series, 6 of whom were long-term survivors of malignant, non-hepatic tumors, underwent either a biopsy or a complete excision to obtain the diagnosis. The imaging characteristics could not be considered pathognomonic. The lesion remained stable after the biopsy in 8 patients; no complications were observed in other 10 patients who underwent resection of the mass. The outcome of all our patients with or without previous oncological disease was benign.

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