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Methods Enzymol. 2010;470:487-507. doi: 10.1016/S0076-6879(10)70019-7. Epub 2010 Mar 1.

Experimental evolution in yeast: a practical guide.

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1
Department of Genome Sciences, University of Washington, Seattle, Washington, USA.

Abstract

Experimental evolution refers to a broad range of studies in which selection pressures are applied to populations. In some applications, particular traits are desired, while in others the subject of study is the mechanisms of evolution or the different modes of behavior between systems. This chapter will explore the range of studies falling under the experimental evolution umbrella, and their relative merits for different types of applications. Practical aspects of experimental evolution will also be discussed, including commercial suppliers, analysis methods, and best laboratory practices.

PMID:
20946822
DOI:
10.1016/S0076-6879(10)70019-7
[Indexed for MEDLINE]
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