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Nat Biotechnol. 2010 Oct;28(10):1049-52. doi: 10.1038/nbt1010-1049.

Epigenomics reveals a functional genome anatomy and a new approach to common disease.

Author information

1
Center for Epigenetics and Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. afeinberg@jhu.edu

Abstract

Epigenomics provides the context for understanding the function of genome sequence, analogous to the functional anatomy of the human body provided by Vesalius a half-millennium ago. Much of the seemingly inconclusive genetic data related to common diseases could therefore become meaningful in an epigenomic context.

PMID:
20944596
PMCID:
PMC2956605
DOI:
10.1038/nbt1010-1049
[Indexed for MEDLINE]
Free PMC Article

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