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Org Biomol Chem. 2010 Dec 7;8(23):5280-4. doi: 10.1039/c0ob00379d. Epub 2010 Oct 11.

3-Methoxalylchromone--a novel versatile reagent for the regioselective purine isostere synthesis.

Author information

1
Institut für Chemie, Universität Rostock, Albert-Einstein-Str. 3a, 18059 Rostock, Germany.

Abstract

The first synthesis of 3-methoxalylchromone was described. The reaction of the latter with electron-rich aminoheterocycles afforded a set of heteroannelated pyridines bearing a CO(2)Me substituent located at the α-position of the pyridine core.

PMID:
20938501
DOI:
10.1039/c0ob00379d
[Indexed for MEDLINE]

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