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Nucleic Acids Res. 2011 Jan;39(Database issue):D997-1001. doi: 10.1093/nar/gkq912. Epub 2010 Oct 11.

T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research.

Author information

1
Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge CB2 0XY, UK. oliver.burren@cimr.cam.ac.uk

Abstract

T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research across mouse, rat and human and presents this to the user as a set of web pages and tools. This update describes the incorporation of new data sets, tools and curation efforts as well as a new website design to simplify site use. New data sets include curated summary data from four genome-wide association studies relevant to T1D, HaemAtlas-a data set and tool to query gene expression levels in haematopoietic cells and a manually curated table of human T1D susceptibility loci, incorporating genetic overlap with other related diseases. These developments will continue to support T1D research and allow easy access to large and complex T1D relevant data sets.

PMID:
20937630
PMCID:
PMC3013780
DOI:
10.1093/nar/gkq912
[Indexed for MEDLINE]
Free PMC Article

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