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Curr Mol Med. 2010 Nov;10(8):756-62.

Potentialities of induced pluripotent stem (iPS) cells for treatment of diseases.

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Medical Biotechnology Div., School of Bio- Science and Technology, VIT University, Vellore-632014, TN, India.


Induced pluripotent stem (iPS) cell research has been growing a new height throughout the world due to its potentialities in medical applications. We can explore several therapeutic applications through the iPS cell research. In this review, we have first discussed the development of iPS cells, reprogramming factors, and effectiveness of iPS cells. Then we have emphasized the potential applications of iPS cells in pharmaceutical and medical sectors, such as, study of cellular mechanisms for spectrum of disease entities, disease-specific iPS cell lines for drugs discovery and development, toxicological studies of drugs development, personalized medicine, and regenerative medicine.

[Indexed for MEDLINE]

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