Format

Send to

Choose Destination
Nat Neurosci. 2010 Nov;13(11):1354-6. doi: 10.1038/nn.2654. Epub 2010 Oct 10.

The habenula is crucial for experience-dependent modification of fear responses in zebrafish.

Author information

1
RIKEN Brain Science Institute, Wako, Saitama, Japan.

Abstract

The zebrafish dorsal habenula (dHb) shows conspicuous asymmetry in its connection with the interpeduncular nucleus (IPN) and is equivalent to the mammalian medial habenula. Genetic inactivation of the lateral subnucleus of dHb (dHbL) biased fish towards freezing rather than the normal flight response to a conditioned fear stimulus, suggesting that the dHbL-IPN pathway is important for controlling experience-dependent modification of fear responses.

PMID:
20935642
DOI:
10.1038/nn.2654
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center