Format

Send to

Choose Destination
Nat Prod Rep. 2011 Jan;28(1):26-47. doi: 10.1039/c0np00017e. Epub 2010 Oct 7.

Bringing natural products into the fold - exploring the therapeutic lead potential of secondary metabolites for the treatment of protein-misfolding-related neurodegenerative diseases.

Author information

1
Natural Products Discovery Group, Department of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, Norman, OK, 73019-5251, USA.

Abstract

A review with 187 references, describing natural products that exhibit bioactive properties relevant to the treatment of protein aggregation-related neurodegenerative diseases (e.g., Huntington's, Parkinson's, and prion diseases) and comparing the chemical properties of these secondary metabolite leads to compounds in clinical use for treating central nervous system conditions.

PMID:
20927454
DOI:
10.1039/c0np00017e
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Royal Society of Chemistry
Loading ...
Support Center