Format

Send to

Choose Destination
Brain Res. 2010 Dec 10;1364:10-24. doi: 10.1016/j.brainres.2010.09.066. Epub 2010 Nov 1.

Identified GnRH neuron electrophysiology: a decade of study.

Author information

1
Department of Molecular and Integrative Physiology, 7725 Med Sci II, 1301 E Catherine St., Ann Arbor, MI 48109-5622, USA. smoenter@umich.edu

Abstract

Over the past decade, the existence of transgenic mouse models in which reporter genes are expressed under the control of the gonadotropin-releasing hormone (GnRH) promoter has made possible the electrophysiological study of these cells. Here, we review the intrinsic and synaptic properties of these cells that have been revealed by these approaches, with a particular regard to burst generation. Advances in our understanding of neuromodulation of GnRH neurons and synchronization of this network are also discussed.

PMID:
20920482
PMCID:
PMC2992586
DOI:
10.1016/j.brainres.2010.09.066
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center