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J Obstet Gynecol Neonatal Nurs. 2010 Sep-Oct;39(5):525-35. doi: 10.1111/j.1552-6909.2010.01169.x.

The effects of prenatal secondhand smoke exposure on preterm birth and neonatal outcomes.

Author information

1
College of Nursing, University of Kentucky, Lexington, KY 40536-0232, USA. kristin.ashford@uky.edu

Erratum in

  • J Obstet Gynecol Neonatal Nurs. 2011 May;40(3):386.

Abstract

OBJECTIVE:

To examine the relationship between prenatal secondhand smoke (SHS) exposure, preterm birth and immediate neonatal outcomes by measuring maternal hair nicotine.

DESIGN:

Cross-sectional, observational design.

SETTING:

A metropolitan Kentucky birthing center.

PARTICIPANTS:

Two hundred and ten (210) mother-baby couplets.

METHODS:

Nicotine in maternal hair was used as the biomarker for prenatal SHS exposure collected within 48 hours of birth. Smoking status was confirmed by urine cotinine analysis.

RESULTS:

Smoking status (nonsmoking, passive smoking, and smoking) strongly correlated with low, medium, and high hair nicotine tertiles (ρ=.74; p<.001). Women exposed to prenatal SHS were more at risk for preterm birth (odds ratio [OR]=2.3; 95% Confidence Interval [CI] [.96, 5.96]), and their infants were more likely to have immediate newborn complications (OR=2.4; 95% CI [1.09, 5.33]) than nonexposed women. Infants of passive smoking mothers were at increased risk for respiratory distress syndrome (RDS) (OR=4.9; 95% CI [1.45, 10.5]) and admission to a Neonatal Intensive Care Unit (NICU) (OR=6.5; CI [1.29, 9.7]) when compared to infants of smoking mothers (OR=3.9; 95% CI [1.61, 14.9]; OR=3.5; 95% CI [2.09, 20.4], respectively). Passive smokers and/or women with hair nicotine levels greater than .35 ng/ml were more likely to deliver earlier (1 week), give birth to infants weighing less (decrease of 200-300 g), and deliver shorter infants (decrease of 1.1-1.7 cm).

CONCLUSIONS:

Prenatal SHS exposure places women at greater risk for preterm birth, and their newborns are more likely to have RDS, NICU admissions, and immediate newborn complications.

PMID:
20919999
PMCID:
PMC2951268
DOI:
10.1111/j.1552-6909.2010.01169.x
[Indexed for MEDLINE]
Free PMC Article

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