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NMR Biomed. 2010 Aug;23(7):781-93. doi: 10.1002/nbm.1509.

Steady-state diffusion-weighted imaging: theory, acquisition and analysis.

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1
Centre for Functional MRI of the Brain (FMRIB), University of Oxford, Oxford, UK.

Abstract

Steady-state diffusion-weighted imaging (DWI) has long been recognized to offer potential benefits over conventional spin-echo methods. This family of pulse sequences is highly efficient and compatible with three-dimensional acquisitions, which could enable high-resolution, low-distortion images. However, the same properties that lead to its efficiency make steady-state imaging highly susceptible to motion and create a complicated signal with dependence on T(1), T(2) and flip angle. Recent developments in gradient hardware, motion-mitigation techniques and signal analysis offer potential solutions to these problems, reviving interest in steady-state DWI. This review offers a description of steady-state DWI signal formation and provides an overview of the current methods for steady-state DWI acquisition and analysis.

PMID:
20886565
DOI:
10.1002/nbm.1509
[Indexed for MEDLINE]
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