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Cardiol Res Pract. 2010 Aug 29;2011. pii: 587650. doi: 10.4061/2011/587650.

Passive smoking and the development of cardiovascular disease in children: a systematic review.

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School of Sport, Performing Arts and Leisure, University of Wolverhampton, Walsall, West Midlands WS1 3BD, UK.


Passive smoking may be implicated in the development of cardiovascular disease (CVD) in children because of their partially developed physiological systems. The aim of the present systematic paper is to investigate whether passive smoking is associated with factors that influence the development of CVD in children. Data sources included Medline, Cochrane Library, Cumulative Index to Nursing & Allied Health (CINAHL) research database, Google Scholar, Excerpta Medica database (EMBASE), the 2006 Office of the Surgeon General's report, and the 2005 report from the California Environmental Protection Agency. We identified a total of 42 relevant articles (i.e., 30 reviews and 12 observational). Results revealed that passive smoking may be implicated in deteriorating cardiovascular status in children in terms of unfavorable high-density lipoprotein levels and deteriorated vascular function.

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