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Rev Neurosci. 2010;21(3):223-37.

Structure and function relationships during ocular dominance plasticity in the visual cortex.

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Department of Molecular Visual Plasticity, Netherlands Institute for Neuroscience an Institute of the Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands.


Our ability to learn relies on the potential of the neocortex to change its neuronal circuits through experience. This change is mediated by the loss or formation of synaptic contacts or the adjustment of their synaptic strength. In recent decades, the primary visual cortex has proven an excellent system for studying structure/function relationships during plasticity in the neocortex. Here we describe current knowledge about the structural changes in inhibitory or excitatory synapses that accompany experience dependent plasticity in the visual cortex. We discuss unresolved issues and technical developments that will help to provide answers in the near future.

[Indexed for MEDLINE]

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