Format

Send to

Choose Destination

A generative model for brain tumor segmentation in multi-modal images.

Author information

1
1 Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, USA.

Abstract

We introduce a generative probabilistic model for segmentation of tumors in multi-dimensional images. The model allows for different tumor boundaries in each channel, reflecting difference in tumor appearance across modalities. We augment a probabilistic atlas of healthy tissue priors with a latent atlas of the lesion and derive the estimation algorithm to extract tumor boundaries and the latent atlas from the image data. We present experiments on 25 glioma patient data sets, demonstrating significant improvement over the traditional multivariate tumor segmentation.

PMID:
20879310
PMCID:
PMC3050038
DOI:
10.1007/978-3-642-15745-5_19
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center