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J Cataract Refract Surg. 2010 Oct;36(10):1786-9. doi: 10.1016/j.jcrs.2010.06.046.

Surgically induced corneal necrotizing keratitis following LASIK in a patient with inflammatory bowel disease.

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London Vision Clinic, London, United Kingdom.


We describe a case of necrotizing keratitis that developed after laser in situ keratomileusis (LASIK) in a 50-year-old woman with inflammatory bowel disease. The patient had not disclosed her history of a total colectomy for recurrent ulcerative colitis and developed bilateral stromal inflammation and corneal melting along the flap edge with ulceration within 3 days of uneventful bilateral LASIK for myopia. She was aggressively managed with topical and systemic corticosteroid therapy. Flap infiltrates gradually resolved, with no relapse during the 12-month follow-up. This case highlights the importance of taking a detailed history, specifically addressing autoimmune diseases, before corneal refractive surgery.

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