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Vaccine. 2011 Jan 29;29(5):886-9. doi: 10.1016/j.vaccine.2010.09.020. Epub 2010 Sep 23.

Guillain-Barré syndrome after Gardasil vaccination: data from Vaccine Adverse Event Reporting System 2006-2009.

Author information

1
Department of Neurology, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA. souayani@umdnj.edu

Abstract

Using data from Vaccine Adverse Event Reporting System, we identified 69 reports of Guillain-Barré Syndrome (GBS) after Gardasil vaccination that occurred in the United States between 2006 and 2009. The onset of symptoms was within 6 weeks after vaccination in 70% of the patients in whom the date of vaccination was known. The estimated weekly reporting rate of post-Gardasil GBS within the first 6 weeks (6.6 per 10,000,000) was higher than that of the general population, and higher than post-Menactra and post-influenza vaccinations. Further prospective active surveillance for accurate ascertainment and identification of high-risk groups of GBS after Gardasil vaccination is warranted.

PMID:
20869467
DOI:
10.1016/j.vaccine.2010.09.020
[Indexed for MEDLINE]

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