Format

Send to

Choose Destination
Radiol Clin North Am. 2010 Sep;48(5):1075-88. doi: 10.1016/j.rcl.2010.07.017.

Molecular imaging of the breast.

Author information

1
Division of Breast Imaging, Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02129, USA. rbirdwell@partners.org

Abstract

Contrast-enhanced magnetic resonance imaging (MRI), MR spectroscopy, and nuclear medicine sestamibi imaging using technetium-99m methoxyisobutyl isonitrile or positron emission tomography (PET) techniques provide information beyond that of structural imaging by displaying tumor neoangiogenesis, tumor metabolites, increased numbers of tumor cellular mitochondria, and hypermetabolic tumor cells. Much needs to be learned at the molecular level of normal cellular pathways either suppressed or enhanced by tumor-specific molecular changes. These discoveries will allow realization of true individualized patient tumor detection, treatment, and surveillance.

Republished from

PMID:
20868901
DOI:
10.1016/j.rcl.2010.07.017

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center