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Ann Thorac Surg. 2010 Oct;90(4):1384-90. doi: 10.1016/j.athoracsur.2010.04.037.

Off-pump coronary artery bypass surgery versus percutaneous coronary intervention: a meta-analysis of randomized and nonrandomized studies.

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Cardiothoracic Surgical Unit, Royal Prince Alfred Hospital, Baird Institute, Faculty of Medicine, University of Sydney, Sydney, Australia.


We performed a meta-analysis of all studies comparing off-pump coronary artery bypass graft surgery (OPCABG) and percutaneous coronary intervention (PCI) for patients with coronary artery disease. Ten studies were included in the meta-analysis and 4,821 patients were compared, of whom 3,450 patients underwent PCI and 1,371 patients underwent OPCABG. The rates of stroke, myocardial infarction, cardiac mortality, and all-cause mortality were similar. The 12-month rate of major adverse cardiac or cerebrovascular events and need for repeat revascularization was significantly lower in the OPCABG group when compared with the PCI group.

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