Pregnancy a short time after multimodal therapy for bilateral breast cancer: a case report and review of literature

J Oncol Pharm Pract. 2011 Dec;17(4):440-3. doi: 10.1177/1078155210384755. Epub 2010 Sep 21.

Abstract

Pregnancy occurring after multimodal therapy in a woman with breast cancer with a 1-year follow-up period is a relatively rare condition and has been defined as pregnancy-associated breast cancer. A patient can become pregnant after chemotherapy for breast cancer while she is on tamoxifen. However, the effects of tamoxifen on fetus and on the course of the pregnancy are still unknown. Here, we present a 39-year-old woman treated with chemotherapy and radiotherapy for bilateral breast cancer, and who became pregnant while taking tamoxifen.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / therapy*
  • Combined Modality Therapy / adverse effects
  • Combined Modality Therapy / methods*
  • Female
  • Goserelin / adverse effects
  • Goserelin / therapeutic use
  • Humans
  • Infant, Newborn
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnosis*
  • Pregnancy Complications, Neoplastic / drug therapy
  • Pregnancy Complications, Neoplastic / therapy*
  • Tamoxifen / adverse effects
  • Tamoxifen / therapeutic use
  • Time Factors

Substances

  • Tamoxifen
  • Goserelin