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Sex Transm Infect. 2011 Feb;87(1):38-40. doi: 10.1136/sti.2010.044487. Epub 2010 Sep 18.

Association of Mycoplasma genitalium with balanoposthitis in men with non-gonococcal urethritis.

Author information

1
Department of Social Medicine, School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol BS8 2PS, UK. Paddy.horner@bristol.ac.uk

Abstract

OBJECTIVE:

To determine whether Mycoplasma genitalium is associated with balanitis and/or posthitis in a previous study of the role of M genitalium in men with acute non-gonococcal urethritis (NGU).

METHODS:

In a previous study of men with acute NGU, the existence of balanitis and/or posthitis was recorded. Chlamydia trachomatis, M genitalium and ureaplasmas were sought in urethral swabs and urine using a direct fluorescent antibody test and in-house PCR, an in-house PCR and a culture method, respectively. Men were treated with doxycycline or erythromycin.

RESULTS:

M genitalium was associated significantly (p = 0.01) with balanitis and/or posthitis in 114 men with acute NGU. This association persisted when there was control for C trachomatis and urethral discharge (p = 0.021, OR 4.1, 95% CI 1.2 to 13.5). C trachomatis and ureaplasmas were not associated with balanitis and/or posthitis.

CONCLUSION:

Detection of M genitalium in men with acute NGU was associated significantly with balanitis and/or posthitis. The association is biologically plausible and may have a role in HIV-1 transmission and susceptibility.

PMID:
20852310
DOI:
10.1136/sti.2010.044487
[Indexed for MEDLINE]

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