Format

Send to

Choose Destination
See comment in PubMed Commons below
Int J Hyperthermia. 2010;26(7):699-709. doi: 10.3109/02656736.2010.493915.

Present and future technology for simultaneous superficial thermoradiotherapy of breast cancer.

Author information

1
Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. EMoros@uams.edu

Abstract

This paper reviews systems and techniques to deliver simultaneous thermoradiotherapy of breast cancer. It first covers the clinical implementation of simultaneous delivery of superficial (microwave or ultrasound) hyperthermia and external photon beam radiotherapy, first using a Cobalt-60 teletherapy unit and later medical linear accelerators. The parallel development and related studies of the Scanning Ultrasound Reflector Linear Arrays System (SURLAS), an advanced system specifically designed and developed for simultaneous thermoradiotherapy, follows. The performance characteristics of the SURLAS are reviewed and power limitation problems at high acoustic frequencies (>3 MHz) are discussed along with potential solutions. Next, the feasibility of simultaneous SURLAS hyperthermia and intensity modulated radiation therapy/image-guided radiotherapy (IMRT/IGRT) is established based on published and newly presented studies. Finally, based on the encouraging clinical results thus far, it is concluded that new trials employing the latest technologies are warranted along with further developments in treatment planning.

PMID:
20849263
PMCID:
PMC2943851
DOI:
10.3109/02656736.2010.493915
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis Icon for PubMed Central
    Loading ...
    Support Center