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Arch Virol. 2010 Dec;155(12):2035-9. doi: 10.1007/s00705-010-0791-0. Epub 2010 Sep 15.

Persistence in darkness of virulent alphaviruses, Ebola virus, and Lassa virus deposited on solid surfaces.

Author information

1
Edgewood Chemical Biological Center, 5183 Blackhawk Road (RDCB-DR) Aberdeen Proving Ground, Maryland 21010-5424, USA. joseluis.sagripanti@us.army.mil

Abstract

Ebola, Lassa, Venezuelan equine encephalitis, and Sindbis viruses were dried onto solid surfaces, incubated for various time periods under controlled conditions of temperature and relative humidity, and quantitatively eluted from surfaces, and viral titers in the recovered samples were determined. The viral inactivation kinetics that were obtained indicated that viral resistance to natural inactivation in the dark follows (in decreasing order of stability) alphavirus > Lassa virus > Ebola virus. The findings reported in this study on the natural decay in the dark should assist in understanding the biophysical properties of enveloped RNA viruses outside the host and in estimating the persistence of viruses in the environment during epidemics or after an accidental or intentional release.

PMID:
20842393
DOI:
10.1007/s00705-010-0791-0
[Indexed for MEDLINE]

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