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Antimicrob Agents Chemother. 2010 Dec;54(12):5381-6. doi: 10.1128/AAC.00728-10. Epub 2010 Sep 13.

Comparative in vitro activities of torezolid (DA-7157) against clinical isolates of aerobic and anaerobic bacteria in South Korea.

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1
Department of Clinical Laboratory Science, Dong-eui University, Busan, South Korea.

Abstract

Resistance of Gram-positive pathogens to first-line antimicrobial agents has been increasing in many parts of the world. We compared the in vitro activities of torezolid with those of other antimicrobial agents, including linezolid, against clinical isolates of major aerobic and anaerobic bacteria. Torezolid had an MIC(90) of ≤0.5 μg/ml for the Gram-positive bacterial isolates tested and was more potent than either linezolid or vancomycin.

PMID:
20837761
PMCID:
PMC2981271
DOI:
10.1128/AAC.00728-10
[Indexed for MEDLINE]
Free PMC Article
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