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Int J Public Health. 2011 Apr;56(2):231-5. doi: 10.1007/s00038-010-0183-y. Epub 2010 Sep 11.

Hypertension and risk of death from external causes in the Physicians' Health Study enrollment cohort.

Author information

1
Department of Public Health, University of Tennessee, Knoxville, TN, USA. pdterry@utk.edu

Abstract

OBJECTIVES:

To address the recent hypothesis that hypertension increases the risk of death from external causes.

METHODS:

We examined blood pressure and death from external causes among 82,037 male physicians who were screened for eligibility to enroll in the Physicians' Health Study.

RESULTS:

During up to 6.6 years of mortality follow-up, there were 304 deaths from external causes. No association was found overall, although we observed an increased risk of non-passive external causes of death, particularly death due to falls, which was independent of various lifestyle, medical, and pharmacological risk factors.

CONCLUSIONS:

The results of our study support this novel hypothesis. Further studies are needed to explore potential causal mechanisms between elevated BP and the risk of external death.

PMID:
20835747
PMCID:
PMC3024448
DOI:
10.1007/s00038-010-0183-y
[Indexed for MEDLINE]
Free PMC Article

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