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Indian J Nephrol. 2010 Apr;20(2):94-6. doi: 10.4103/0971-4065.65304.

Complete remission of lambda light chain myeloma presenting with acute renal failure following treatment with bortezomib and steroids.

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Department of Nephrology, Lilavati Hospital and Research Centre, Mumbai, India.


About one in five people with multiple myeloma produce only light chains. Patients with lambda light chain disease have a three times worse prognosis than kappa light chain disease. We report a case of lambda light chain deposition disease in a 35-year-old female who presented with acute renal failure requiring hemodialysis. She had complete recovery and is now in complete remission following treatment with bortezomib and steroids.


Acute renal failure; bortezomib; lambda and kappa light chains; multiple myeloma; steroids

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