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Psychosomatics. 2010 Sep-Oct;51(5):370-6. doi: 10.1176/appi.psy.51.5.370.

Management of psychosis associated with a prolactinoma: case report and review of the literature.

Author information

1
McLean Hospital, Boston, MA, USA. alishir@pi.cpmc.columbia.edu

Abstract

BACKGROUND:

Prolactinomas are the most common pituitary tumors; they are treated with dopamine agonists, which may cause psychotic symptoms as a side effect. Psychosis is treated with dopamine-receptor blockers that may result in elevated serum prolactin and symptomatic hyperprolactinemia.

OBJECTIVE:

The authors will review a case of a patient with a prolactinoma as well as schizophrenia and illustrate the management of psychosis in this case.

METHOD:

The review describes the management of prolactinoma, symptoms of hyperprolactinemia, and long-term effects of hyperprolactinemia.

RESULTS:

In the case presentation reviewed, the patient was finally discharged on risperidone long-acting injection and testosterone supplementation, with no growth of the adenoma after 3 years.

DISCUSSION:

This review provides recommendations and treatment strategy for management of prolactinoma in a patient with schizophrenia.

PMID:
20833935
PMCID:
PMC3667992
DOI:
10.1176/appi.psy.51.5.370
[Indexed for MEDLINE]
Free PMC Article

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