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Curr Biol. 2010 Sep 14;20(17):R780-5. doi: 10.1016/j.cub.2010.07.007.

Evolution of eukaryotic DNA methylation and the pursuit of safer sex.

Author information

1
Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA.

Abstract

Cytosine methylation is an ancient process with conserved enzymology but diverse biological functions that include defense against transposable elements and regulation of gene expression. Here we will discuss the evolution and biological significance of eukaryotic DNA methylation, the likely drivers of that evolution, and major remaining mysteries.

PMID:
20833323
DOI:
10.1016/j.cub.2010.07.007
[Indexed for MEDLINE]
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