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Curr Biol. 2010 Sep 14;20(17):R697-9. doi: 10.1016/j.cub.2010.07.035.

Gene regulation: enhancers stepping out of the shadow.

Author information

1
Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University Medical Center, New York, NY 10032, USA. or38@columbia.edu

Abstract

The expression of many animal genes has been shown to be controlled by two--rather than one--enhancers with similar regulatory content. Such enhancer redundancy ensures robustness of gene expression under adverse environmental or genetic conditions.

PMID:
20833307
DOI:
10.1016/j.cub.2010.07.035
[Indexed for MEDLINE]
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