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Expert Rev Clin Immunol. 2010 Sep;6(5):745-56. doi: 10.1586/eci.10.64.

Duloxetine for the treatment of fibromyalgia.

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1
Oregon Health and Science University, School of Nursing, Portland, OR 97239, USA. wrightch@ohsu.edu

Abstract

This article presents a brief review of the physiologic abnormalities seen in fibromyalgia, current theories of widespread pain, and treatment options, including emerging therapeutics, with a focus on the use of duloxetine to manage fibromyalgia symptoms. Major clinical trials that examine the efficacy and effectiveness of duloxetine to date are reviewed, and safety issues are discussed.

PMID:
20828282
PMCID:
PMC3056054
DOI:
10.1586/eci.10.64
[Indexed for MEDLINE]
Free PMC Article
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