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Methods Mol Biol. 2010;662:79-95. doi: 10.1007/978-1-60761-800-3_4.

Systems biology of cell behavior.

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1
Systems Biology Lab, Department of Engineering, University of Leicester, Leicester, UK.

Abstract

Systems Biology approaches to drug discovery largely focus on the increasing understanding of intracellular and cellular circuits, by computational representation of a molecular system followed by parameter validation against experimental data. This chapter outlines a universal approach to systems biology that allows the linking of intracellular molecular machinery and cellular activity. This procedure is achieved by applying mathematical modeling to molecular modules of a cell in the light of systems biology techniques.

PMID:
20824467
DOI:
10.1007/978-1-60761-800-3_4
[Indexed for MEDLINE]
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