Format

Send to

Choose Destination
Antimicrob Agents Chemother. 2010 Nov;54(11):4914-6. doi: 10.1128/AAC.00878-10. Epub 2010 Sep 7.

Emergence of metallo-β-lactamase NDM-1-producing multidrug-resistant Escherichia coli in Australia.

Author information

1
Service de Bactériologie-Virologie, INSERM U914, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, 78 rue du Général Leclerc, Le Kremlin-Bicêtre cedex, France.

Abstract

A multidrug-resistant Escherichia coli isolate recovered in Australia produced a carbapenem-hydrolyzing β-lactamase. Molecular investigations revealed the first identification of the bla(NDM-1) metallo-β-lactamase gene in that country. In addition, this E. coli isolate expressed the extended-spectrum β-lactamase CTX-M-15, together with two 16S rRNA methylases, namely, ArmA and RmtB, conferring a high level of resistance to aminoglycosides.

PMID:
20823289
PMCID:
PMC2976126
DOI:
10.1128/AAC.00878-10
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center