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Free Radic Res. 2010 Sep;44(9):971-82. doi: 10.3109/10715762.2010.500328.

Recent advances in hydrogen research as a therapeutic medical gas.

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Department of Surgery, Taipei-Veterans General Hospital and National Yang-Ming University School of Medicine, Taiwan.


Recent basic and clinical research has revealed that hydrogen is an important physiological regulatory factor with antioxidant, anti-inflammatory and anti-apoptotic protective effects on cells and organs. Therapeutic hydrogen has been applied by different delivery methods including straightforward inhalation, drinking hydrogen dissolved in water and injection with hydrogen-saturated saline. This review summarizes currently available data regarding the protective role of hydrogen, provides an outline of recent advances in research on the use of hydrogen as a therapeutic medical gas in diverse models of disease and discusses the feasibility of hydrogen as a therapeutic strategy. It is not an overstatement to say that hydrogen's impact on therapeutic and preventive medicine could be enormous in the future.

[Indexed for MEDLINE]

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