Abstract
Five new metabolites, fusaranthraquinone (1), fusarnaphthoquinones A-C (2-4), and fusarone (5), were isolated from the sea fan-derived fungi Fusarium spp. PSU-F14 and PSU-F135 along with 18 known compounds. The structures were elucidated on the basis of spectroscopic evidence. Their antibacterial, antifungal, antimycobacterial, antimalarial, and cytotoxic activities were examined.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Anthozoa / microbiology*
-
Anthraquinones / chemistry
-
Anthraquinones / isolation & purification*
-
Anthraquinones / pharmacology*
-
Anti-Bacterial Agents / chemistry
-
Anti-Bacterial Agents / isolation & purification*
-
Anti-Bacterial Agents / pharmacology*
-
Antifungal Agents / chemistry
-
Antifungal Agents / isolation & purification*
-
Antifungal Agents / pharmacology*
-
Antimalarials / chemistry
-
Antimalarials / isolation & purification*
-
Antimalarials / pharmacology*
-
Antineoplastic Agents / chemistry
-
Antineoplastic Agents / isolation & purification*
-
Antineoplastic Agents / pharmacology*
-
Chlorocebus aethiops
-
Cyclopentanes / chemistry
-
Cyclopentanes / isolation & purification*
-
Cyclopentanes / pharmacology*
-
Drug Screening Assays, Antitumor
-
Fusarium / chemistry*
-
Humans
-
KB Cells
-
Microbial Sensitivity Tests
-
Molecular Structure
-
Mycobacterium tuberculosis / drug effects
-
Naphthoquinones / chemistry
-
Naphthoquinones / isolation & purification*
-
Naphthoquinones / pharmacology*
-
Nuclear Magnetic Resonance, Biomolecular
-
Oceans and Seas
-
Plasmodium falciparum / drug effects
-
Vero Cells
Substances
-
Anthraquinones
-
Anti-Bacterial Agents
-
Antifungal Agents
-
Antimalarials
-
Antineoplastic Agents
-
Cyclopentanes
-
Naphthoquinones
-
cyclopentanone