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Clin Perinatol. 2010 Sep;37(3):547-63. doi: 10.1016/j.clp.2010.06.004.

Antibiotic resistance in neonatal intensive care unit pathogens: mechanisms, clinical impact, and prevention including antibiotic stewardship.

Author information

1
Department of Pediatrics, Columbia University, 622 West 168th Street, PH4W-475, New York, NY 10032, USA.

Abstract

Antimicrobial-resistant pathogens are of increasing concern in the neonatal intensive care unit population. A myriad of resistance mechanisms exist in microorganisms, and management can be complex because broad-spectrum antibiotics are increasingly needed. Control and prevention of antibiotic-resistant organisms (AROs) require an interdisciplinary team with continual surveillance. Judicious use of antibiotics; minimizing exposure to risk factors, when feasible; and effective hand hygiene are crucial interventions to reduce infection and transmission of AROs.

PMID:
20813270
PMCID:
PMC4440667
DOI:
10.1016/j.clp.2010.06.004
[Indexed for MEDLINE]
Free PMC Article

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