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Nature. 1978 Jun 29;273(5665):718-23.

Alterations in the surface properties of cells responsive to nerve growth factor.

Abstract

An initial effect of nerve growth factor on a responsive nerve cell line is to increase intracellular cyclic AMP, which in turn leads to a mobilisation of calcium ions. These events are correlated with structural changes in the plasma membrane, increased cell-substratum adhesion, and neurite outgrowth.

PMID:
208002
DOI:
10.1038/273718a0
[Indexed for MEDLINE]

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