Naringin and vitamin E influence the oxidative stability and lipid profile of plasma in lambs fed fish oil

Res Vet Sci. 2011 Aug;91(1):98-102. doi: 10.1016/j.rvsc.2010.07.028. Epub 2010 Aug 25.

Abstract

Thirty two Merino lambs (15 weeks old) fed barley straw and fish oil enriched concentrate were used to assess the effect of vitamin E (6 g kg(-1) DM) and naringin (1.5-3 g kg(-1) DM) on plasma lipid peroxidation (TBARS), total antioxidant status (TAS), immune response, plasma cholesterol, and triglycerides. After 21 days feeding the experimental diets, lambs were subjected to a 4 h transportation stress period and then held 4 more hours without feed. TBARS values before stress were lower for animals consuming vitamine E and naringin when compared to control lambs (P<0.05). However, after stress all groups presented similar levels of TBARS. TAS decreased (P<0.05) in all groups in response to stress with values recovering (P<0.05) to pre-stress values following 4 h of rest. A rise (P<0.05) in serum concentrations of triacylglycerol following 21 d of fish oil supplementation was dampened in lambs consuming vitamin E or naringin. Both pre-stress TBARS and triacylglycerol-reducing effects of naringin added to fish oil enriched concentrate for fattening lambs are reported.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animal Feed
  • Animal Nutritional Physiological Phenomena / drug effects
  • Animals
  • Antioxidants / administration & dosage
  • Antioxidants / metabolism
  • Antioxidants / pharmacology*
  • Cholesterol / blood
  • Diet
  • Dietary Supplements*
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule / veterinary
  • Fish Oils / administration & dosage*
  • Flavanones / administration & dosage
  • Flavanones / pharmacology*
  • Hordeum
  • Immune System Phenomena / drug effects
  • Lipid Peroxidation / drug effects
  • Lipids / blood*
  • Random Allocation
  • Sheep, Domestic / immunology
  • Sheep, Domestic / physiology*
  • Skinfold Thickness
  • Stress, Physiological
  • Triglycerides / blood
  • Vitamin E / administration & dosage
  • Vitamin E / pharmacology*

Substances

  • Antioxidants
  • Fish Oils
  • Flavanones
  • Lipids
  • Triglycerides
  • Vitamin E
  • Cholesterol
  • naringin