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Bioinformatics. 2010 Oct 15;26(20):2635-6. doi: 10.1093/bioinformatics/btq469. Epub 2010 Aug 24.

TFInfer: a tool for probabilistic inference of transcription factor activities.

Author information

1
School of Informatics, University of Edinburgh, 10 Crichton Street, Edinburgh EH8 9AB, UK.

Abstract

SUMMARY:

TFInfer is a novel open access, standalone tool for genome-wide inference of transcription factor activities from gene expression data. Based on an earlier MATLAB version, the software has now been extended in a number of ways. It has been significantly optimised in terms of performance, and it was given novel functionality, by allowing the user to model both time series and data from multiple independent conditions. With a full documentation and intuitive graphical user interface, together with an in-built data base of yeast and Escherichia coli transcription factors, the software does not require any mathematical or computational expertise to be used effectively.

AVAILABILITY:

http://homepages.inf.ed.ac.uk/gsanguin/TFInfer.html

CONTACT:

gsanguin@staffmail.ed.ac.uk

SUPPLEMENTARY INFORMATION:

Supplementary data are available at Bioinformatics online.

PMID:
20739311
DOI:
10.1093/bioinformatics/btq469
[Indexed for MEDLINE]

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