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Med Clin North Am. 2010 Sep;94(5):1003-15. doi: 10.1016/j.mcna.2010.05.001.

The patient with a thyroid nodule.

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  • 1Department of Otolaryngology-Head and Neck Surgery, University of Rochester Medical Center, Box 629, 601 Elmwood Avenue, Rochester, NY 14642, USA.


Nodular thyroid disease is common in the United States and throughout the world. Although most thyroid nodules are benign in nature, certain clinical, radiographic, and cytologic features are associated with an increased risk of malignancy. A clear understanding of these risk factors assists in the decision-making process when evaluating a patient with a thyroid nodule. It is this process that ultimately determines whether or not a patient is referred for surgery. This article provides a framework for clinicians to risk-stratify and appropriately manage patients with thyroid nodules.

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