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Immunity. 2010 Aug 27;33(2):141-3. doi: 10.1016/j.immuni.2010.08.007.

Interferon regulatory factor 4: combinational control of lymphocyte differentiation.

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1
Laboratory of Lymphocyte Signalling and Development, The Babraham Institute, Cambridge, UK. marc.veldhoen@bbsrc.ac.uk

Abstract

Transcriptional mechanisms involved in the differentiation of the recently identified interleukin-9 (IL-9) secreting T helper cell subset are still poorly defined. In this issue of Immunity, Staudt et al. (2010) now report an essential role for the interferon regulatory factor-4 in IL-9 production.

PMID:
20732634
DOI:
10.1016/j.immuni.2010.08.007
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