Format

Send to

Choose Destination
J Mammary Gland Biol Neoplasia. 2010 Sep;15(3):329-39. doi: 10.1007/s10911-010-9188-7. Epub 2010 Aug 24.

Immune cell location and function during post-natal mammary gland development.

Author information

1
Department of Lab Medicine and Pathology, Graduate Program in Microbiology, Immunology and Cancer Biology, Masonic Cancer Center, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

Abstract

Post-natal mammary gland development requires complex interactions between the epithelial cells and various cell types within the stroma. Recent studies have illustrated the importance of immune cells and their mediators during the various stages of mammary gland development. However, the mechanisms by which these immune cells functionally contribute to mammary gland development are only beginning to be understood. This review provides an overview of the localization of immune cells within the mammary gland during the various stages of post-natal mammary gland development. Furthermore, recent studies are summarized that illustrate the mechanisms by which these cells are recruited to the mammary gland and their functional roles in mammary gland development.

PMID:
20730636
PMCID:
PMC4204476
DOI:
10.1007/s10911-010-9188-7
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Springer Icon for PubMed Central
Loading ...
Support Center